In addition, agonism of CB1 receptors leads to the non-competitive inhibition of emetogenic serotonin receptors, resulting in the inhibition of gastric function and proemetic dopamine activity. The biggest risk factor for developing CHS is long-term marijuana use (typically 10 to 12 years). In addition, it is more common in men and what is cannabinoid syndrome in those who’ve been using cannabis since their adolescent years. Intravenous fluids and an antiemetic (medicine to stop vomiting) are two standard approaches, Heard says.

• Also, avoid stressful situations as much as possible, as stress can sometimes worsen CHS symptoms.
• Researchers have identified two receptors called CB1 and CB2 to which marijuana molecules attach.
• People often remain misdiagnosed for years, which delays treatment.
• Untreated CHS can lead to dehydration, electrolyte imbalances, and hospitalization.
• So far, giving up cannabis has been shown to be the only long-term solution.

What is Cannabis Syndrome?

Clinicians should be vigilant about the potential for psychosis to emerge during cannabis withdrawal, especially in heavy users. The high proportion of cases experiencing severe sleep disturbances prior to psychosis onset highlights a potential mechanism linking withdrawal to psychotic symptoms. Doctors may be noticing more cases over the last few years because more states have legalized marijuana, and there’s been an increased focus on possible medical effects, Marino said. THC potency has also increased over the years, which some doctors link to the digestive upset. He advised people with symptoms to go to the hospital because dehydration and potential resulting kidney damage are risks of trying to manage the illness at home. The biggest risk factor for CHS is heavy cannabis use, as in almost daily or multiple times per day over several years.

What is CHS? How nausea, stomach pain led to a diagnosis and link to cannabis

• But occasionally, patients who arrive at a hospital with what initially looks like CHS can instead have pancreatitis, gastritis, gastrointestinal reflux disease (GERD), appendicitis, or other problems.
• Most sufferers report an unusual home treatment–taking long, hot showers or baths–temporarily alleviates these symptoms.
• Symptoms of CHS typically come on several years after the start of chronic marijuana use.
• CHS is also underdiagnosed because people sometimes use marijuana to suppress nausea and vomiting.

Diagnosing CHS can be challenging due to the overlap with other gastrointestinal and metabolic issues. Physicians typically arrive at a diagnosis by evaluating a patient’s medical history, frequency of cannabis use, and recurring symptoms. When cyclical vomiting syndrome presents similar signs, doctors need to rule out other conditions before confirming CHS.

What are the Phases of Cannabinoid Hyperemesis Syndrome?

A diagnosis of CHS is confirmed if symptoms improve after stopping cannabis use. CHS can also impact mental health, as recurring symptoms may cause anxiety or depression. We are a team of highly trained Psychologists and Psychiatrists who use the most progressive therapeutic treatment approaches, including medication if necessary. People who use marijuana long-term — typically for about 10 to 12 years — are at risk of developing CHS. But not every person who uses marijuana, even long-term use, develops CHS.

How can I prevent cannabinoid hyperemesis syndrome?

Many alcohol rehab people with CHS go to their doctor or an emergency room (ER) for treatment. However, doctors may find it challenging to diagnose the syndrome because people tend not to report their use of marijuana. The only way to end CHS symptoms is to completely stop using all marijuana products. After you quit, you may still have symptoms and side effects for a few days to a few weeks. It’s a serious medical problem that can cause major health issues if you leave it untreated. If you have any symptoms of severe dehydration, like dizziness, confusion and a rapid heartbeat, call 911 right away.